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How an old, rarely prescribed antidepressant was repurposed to treat breast cancer

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Researchers and interns of the Vadlamudi Lab Group at the University of Texas Health Science Center San Antonio, which made the breast cancer treatment breakthrough.
UT Health San Antonio
Researchers and interns of the Vadlamudi Lab Group at the University of Texas Health Science Center at San Antonio, which made the breast cancer treatment breakthrough.

The idea that there may be medicines already out there, safe and approved by the FDA and just waiting to be rediscovered is tantalizing for scientists, doctors, and patients.

Host Bonnie Petrie speaks with a team of researchers at the University of Texas Health Science Center at San Antonio about the story behind their realization that an old, rarely prescribed antidepressant can be repurposed to treat certain types of breast cancer.

Guests:

  • Ratna Vadlamudi, PhD, professor of obstetrics and gynecology and co-leader of the Cancer Development and Progression Program at the Mays Cancer Center.
  • Virginia Kaklamani, MD, leader of the Breast Cancer Program at the Mays Cancer Center and professor of medicine/hematology-oncology at UT Health San Antonio.
  • Arhan Rao, intern at the Vadlamudi lab and student at Health Careers High School.
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