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00000174-b11b-ddc3-a1fc-bfdbb1d30001HearSA is an online audio archive of public programming intended to foster discussion and enhance awareness of informative local presentations and events. The archive includes lectures, panel discussions, book readings, and more. HearSA is presented by Texas Public Radio in association with its local partners. It is important to recognize that the opinions presented in these programs are those of the author or presenter, not Texas Public Radio or any of its stations, and are not necessarily endorsed by TPR.If your organization hosts lectures, book readings, panel discussions, or presentations and is interested in participating, email HearSA curator, Nathan Cone at ncone [at] tpr dot org

Think Science: Longevity

Cyle Perez
Dr. Sara Espinoza, at TPR's Think Science: Longevity panel.

It’s no secret that the U.S. population is aging rapidly. No one is immune. And with aging comes frailty, disease, disabilities, memory loss and more. But what if life could be lived with vigor and vitality throughout your lifespan? What if you could grow older in a healthy and wholesome manner? That’s the goal of UT Health’s Barshop Institute for Longevity and Aging Studies and the subject of this Think Science presentation, held on August 16, 2019. Dr. Sara Espinoza gives an overview of the concerns people have with aging, as well as current research from the Barshop Institute. Dr. Dean Kellogg's presentation delves into the latest findings on use of rapamycin to slow the negative effects of aging in mice, and its potential use in humans.


The panel features two of UT Health's premiere researchers: Dean Kellogg, Ph.D., and Sara E. Espinoza, M.D., M.Sc., AGSF.

Dr. Kellogg's research roles are as the Principal Investigator in several translational projects to explore anti-aging effects of rapamycin, acarbose, and other potential anti-aging pharmaceuticals in humans. These projects involve exploring the effects of anti-aging agents on mechanisms of physical performance, cognitive, and cardiovascular function. In addition, changes in oxidative stress levels and altered skeletal muscle function in human subjects are being explored. Collaborative projects are exploring immunomodulatory effects of rapamycin on responses to vaccines and on overall immunological function in healthy older (70-95yo) volunteers. In addition, he is continuing his work on human cardiovascular and thermoregulatory physiology with studies in spinal cord injured patients in collaborative studies with junior faculty from the Department of Rehabilitation. 

Dr. Espinoza’s research focuses on understanding frailty, an important clinical geriatric syndrome that causes older adults to be at risk for falls, disability, nursing home placement, and death. She highlights diabetes as a major risk factor for frailty and discusses her current study, which is examining whether metformin, a drug commonly used to treat diabetes, can prevent frailty in older adults who have pre-diabetes.

Credit UT Health
Sara E. Espinoza, M.D.

Dr. Espinoza received her medical degree from the University of Virginia and completed her residency at Strong Memorial Hospital, University of Rochester Medical Center. Her clinical fellowship in geriatric medicine was at The Johns Hopkins School of Medicine in Baltimore.

This event was made possible by Baptist Health Foundation of San Antonio, Health Texas, San Antonio Vascular and Endovascular Clinic, and Texas Dermatology.

You can listen to audio from this panel discussion in the embedded link above, and follow along with the presenters' slide programs below.

Improving Health with Aging, by Sara Espinoza, MD, M.Sc. from Nathan Cone

I'm Getting Older! Is there a pill for that? By Dr. Dean Kellogg from Nathan Cone


Nathan has been with TPR since 1995, when he began working on classical music station KPAC 88.3 FM, as host of “Tuesday Night at the Opera.” He soon learned the ropes on KSTX 89.1 FM, and volunteered to work practically any shift that came his way, on either station. He worked in nearly every capacity on the radio before moving into Community Engagement, Marketing, and Digital Media. His reporting and criticism has been honored by the Houston Press Club and Texas Associated Press.