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How The Discovery Of Lithium Transformed Treatment For Bipolar Disorder

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Lithium has been hailed a "miracle drug" for treating bipolar disorder. Walter A. Brown, clinical professor emeritus at Brown University, talks with  Thinkhost Krys Boyd about how the drug has been a transformative treatment for many people with bipolar disorder. 

"The discovery of lithium is often recognized as the so-called start of the psychopharmacological revolution," Brown says. "Before that time, the idea that a drug alone could cure or alleviate a mental illness was just inconceivable. Nobody thought along those lines."

Brown says lithium can be used as a maintenance medication, helping to prevent manic episodes in people with bipolar disorder. Though there can be side effects, he says it's given new hope to many patients.

"If people are untreated... they're going to have an episode of mania and depression every year or so," he says. "With lithium — for those people who respond well to it, and a majority do — those episodes stop, and it really turns their lives around." 

Walter A. Brown’s book is called Lithium: A Doctor, a Drug, and a Breakthrough. Listen to the entire Think conversation here

Copyright 2020 KERA. To see more, visit KERA.

Syeda Hasan is KUT's development and affordability reporter. She previously worked as a reporter at Houston Public Media covering county government, immigrant and refugee communities, homelessness and the Sandra Bland case. Her work has been heard nationally on public radio shows such as Morning Edition, All Things Considered and Marketplace.
Syeda Hasan
Syeda Hasan covers mental health for KERA News. A Houston native, her journalism career has taken her to public radio newsrooms around Texas.