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Since Gen. David Petraeus resigned as the head of the CIA after admitting to an extramarital affair, the scandal has become rich fodder for the opinion pages. NPR's Jacki Lyden reads from a variety of op-eds, and takes calls from listeners on why the story matters.

Maine, Maryland, and Washington passed same-sex marriage on the ballot in the 2012 election. Minnesotans struck down a proposed constitutional amendment that would define marriage as the union of a man and a woman. Now, people on both sides of the issue are reevaluating their strategies.

In her memoir, Susannah Cahalan writes about the month she descended into madness, experiencing seizures, paranoia, psychosis and catatonia. At first, her family was frightened, and her doctors, baffled. The eventual prognosis? A rare autoimmune disease that was attacking her brain.

Retail sales fell in October, largely because of the storm. To get a sense of the small picture — messier, more ambiguous — I visited three small businesses on one hard-hit street.

Sen.-elect Angus King of Maine, who cruised to victory last week running as an independent, said Wednesday that he will caucus with Senate Democrats, giving them in effect a 55-45 seat advantage next year.

Colorado and Washington voted to decriminalize recreational use of marijuana, but that is still illegal at the federal level. Paul and Frank are asking the White House to respect the decision of voters.

The Microsoft executive in charge of bringing Windows 8 to market is out. Steven Sinofsky leaves Microsoft less than three weeks after a major rewrite of the popular operating system was released. Sinofsky had been seen as likely to succeed CEO Steve Ballmer.

Leading GOP senators vow to block U.N. Ambassador Susan Rice from becoming secretary of state if Obama nominates her and object to how she characterized the attack on the U.N. Consulate in Benghazi.

Human-machine integration looms on the horizon, with a promise to redefine who we are as people. Inventor and futurist Ray Kurzweil is an apostle of the coming Singularity, a time when it is envisioned that technology will advance to the point that life is redefined as something other than what we know and experience today.

Some doctors thought Lyme disease was a chronic condition that relapsed. Now, there's evidence that recurring cases of Lyme disease may actually be caused by multiple, discrete tick bites and infections.