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A confirmed case of measles was identified in Atascosa County, south of San Antonio.
County officials made the announcement on Tuesday.
They said the case was confirmed by the Texas Department of State Health Services and was under investigation.
The individual was unvaccinated and may have exposed others to the virus at an evening gathering near Poteet on April 13
The state was also exploring any link to the outbreak in West Texas.
The Atascosa case is the state's latest in the historic outbreak — the worst Texas has seen in 30 years.
The latest from West Texas
The Texas Department of State Health Services confirmed 27 more cases of measles since the update last Friday. The state's updates come every Tuesday and Friday.
That brought the West Texas outbreak to more than 600 cases since the outbreak began in late January.
Sixty-four patients have been hospitalized because of the virus. The state does not track how many are active hospitalizations.
Two school-age children have died from complications from the virus. Both lived in West Texas and were unvaccinated.
Despite claims by Health and Human Services Secretary Robert F. Kennedy Jr., the outbreak is not slowing down.
Health care professionals said the only way to prevent measles is to receive two doses of the MMR vaccine. Measles complications can include pneumonia, hearing loss, meningitis, and death.