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THX mice can be used to study anything that requires a vigorous human immune response, from cancer medications to vaccines and organ transplantation. The mice were created at UT Health San Antonio using human stem cells, but what makes them unique is they also received a dose of estrogen. This is the critical point, according to Dr. Paolo Casali, that leads to the development of a robust human immune system in THX mice.
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Shivani Ruparel, Ph.D., Associate Professor and Director of Research in the Department of Endodontics at UT Health San Antonio, and her team are working on potential analgesics to help mitigate cancer pain.
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The chemical cross-communication between the guts and other organs that occurs when a person metabolizes nutrients begins before we open our mouths, when we see or smell food. The answer to why some people develop obesity, diabetes, and other metabolic disorders, and why some people respond so well to medicines like Ozempic, might lie in those signals. UT Health San Antonio endocrinologist Dr. Marzieh Salehi is studying that communication in patients with spinal cord injury.
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New research from UT Health San Antonio finds a link between obstructive sleep apnea and persistent pain, suggesting that the intermittant lack of oxygen caused by apnea decreases a person's ability to recover from painful stimuli.
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Science & Medicine: Relaxing excited neurons may lead to more effective treatments for schizophreniaA new medication to treat schizophrenia has been developed by scientists who discovered that a neuron that inhibits the activity of other cells may be in short supply in those with the disorder.
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UT Health San Antonio Speech-Language Pathology program graduate students are helping local kids at risk for developing a language disorder through a program called LAUNCH. Angela Kennedy, SLP-D, CCC-SLP, is the director of clinical education and an assistant professor for the Speech-Language Pathology program in the Department of Communication Sciences and Disorders.
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A digital tool that uses artificial intelligence to analyze speech patterns could help doctors detect dementia in patients when other signs and symptoms are not perceptible.
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Up to two percent of Texans have epilepsy. Dr. Charles Szabo at UT Health San Antonio has developed an epilepsy surgery program and is leading groundbreaking research and clinical trials that offer hope to those with the seizure disorder who don't respond to existing medications.
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People who eat a strict keto diet are at risk for an accumulation of aged cells in their organs, but taking intermittent breaks from the diet can prevent these detrimental effects.
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Adam Salmon, PhD, studies aging in marmosets. He and his team recently concluded that an immunosuppressant called rapamycin extends the lifespan of marmosets. This has significant implications for the study of aging in humans.